Purpose: Arterial embolization has been shown to be effective and safe for the management of bleeding, especially for postpartum and pelvic traumatic bleeding. A previous study showed that embolization by suture fragments is possible and effective. We propose to evaluate the efficiency of arterial embolization with non-absorbable suture micro-particle in a porcine model.
Material and Methods: Lower pole of renal arteries in four pigs were embolized: on right side with non-absorbable suture micro-particle (Flexocrin 2®) and on left side with 900 µm micro-particles (Embozene 900®). Pigs were followed for three months (CT at one- and three-months after embolization, digital subtraction angiography at D0 and M3). Histological analyses were realized at M3.
Results: All vascular targets were effectively embolized by non-absorbable suture micro-particles. There was no per- or post-operative complication, especially no infection signs or granuloma in both groups. DSA and CT at three months showed persistent complete embolization of kidney parenchyma associated with a renal atrophy of the embolized area.
Conclusions: Embolization by non-absorbable suture micro-particle (FAIR-Embo concept) is feasible, safe and effective in the medium term, in the porcine model. These results merit considerations for their potential use as an inexpensive and widely available embolization agent in hospitals worldwide.